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 Welcome! to



SIMPAR (Study In Multidisciplinary PAin Research) group was created in 2007 by the Pain Therapy Service of IRCCS Policlinico San Matteo, in collaboration with the Unit of Clinical Pharmacokinetics and the Clinical Epidemiology and Biometric Unit of this hospital and two departments of University of Pavia: The Department of Genetics and Microbiology and the Department of Experimental and Applied Pharmacology, respectively.

The purpose of each analgesic therapy, based on opioids, is the achievement of the best analgesia without side effects. As far, a customized pain therapy considering the clinical aspects, the genetic background and the metabolic capacity of each patient has not been still detected.

To face an innovative approach for patients suffering from acute post-surgical pain or chronic pain (either oncologic or not) the Pain Therapy Service founded the SIMPAR group, to take advantage of the specific competence of different professors in Pavia. The synergy of these units will optimize the management of pain, customizing, by the genetic and pharmacokinetic analysis, the opioid therapies. This will lead to clinical trials with the best benefit and the minor tolerance and/or side effects.


ISURA (International Symposium of Ultrasound for Regional Anesthesia and Pain Medicine) is one of the the largest meeting completely dedicated to the application of ultrasound for regional anesthesia and pain medicine. We are organizing the 14th ISURA in Florence, which was regarded as one of the most beautiful cities in the world by Forbes magazine.

As ultrasound is becoming an important tool in the peri-operative areas as well as pain management, we have assembled a very exciting program to cover various facets of the use of ultrasound, including the use in gastric scanning, airway management, lung and diaphragmatic scan, guidance for regional anesthesia for peri-operative settings, and the application in the chronic pain management.




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